Medicare DPNP
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The Medicare Drug Price Negotiation Program (MDPNP) is a part of the Inflation Reduction Act (IRA) that sets maximum prices for 10 Medicare Part D-covered drugs for 2026, 15 drugs for 2027, and more drugs (including Part B drugs) beginning in 2028. This program will have significant impacts on pharmacy reimbursement and cash flow models.

Pharmacies are not required by CMS to dispense MDPNP drugs, but individual PBM network agreements may require their dispensing. It is critical that pharmacies read their PBM contracts closely to ensure compliance. For more information, click here.


MDPNP Basics

Below are overview resources on the MDPNP program.

Manufacturer Agreements

CMS has provided the list of drug companies that manufacture the selected drugs and will be participating in the MDPNP.

MDPNP Selected Drugs & Negotiated Prices

CMS has provided a list of NDCs that are part of the MDPNP, as well as their negotiated prices.

Pharmacy Resources

Make sure your pharmacy is ready to meet the requirements of the MDPNP, including enrolling in an MTF!